ACMG copilot
Read a variant
Enter one variant. Norn gathers the evidence and drafts a preliminary ACMG classification to confirm.
Example variants
Gather
UrðrLive consequence and frequency from Ensembl VEP and gnomAD v4, with neighbor evidence from ClinVar.
Weigh
VerðandiClaude adjudicates each ACMG criterion against code-computed signals, one line of reasoning each.
Decree
SkuldThe ClinGen points framework combines the verdicts in code. The engine owns the label.